{"id":1833,"date":"2026-09-18T13:32:15","date_gmt":"2026-09-18T04:32:15","guid":{"rendered":"https:\/\/rhanews.co.kr\/?p=1833"},"modified":"2026-09-18T13:32:15","modified_gmt":"2026-09-18T04:32:15","slug":"%ec%97%90%eb%84%88%ec%a7%80%ea%b0%80-%eb%b6%80%ec%a1%b1%ed%95%98%eb%a9%b4-%ec%bc%9c%ec%a7%80%eb%8a%94-%ec%84%b8%ed%8f%ac%ec%9d%98-%eb%b9%84%ec%83%81-%ec%8a%a4%ec%9c%84%ec%b9%98-ampk%eb%8a%94","status":"publish","type":"post","link":"https:\/\/rhanews.co.kr\/?p=1833","title":{"rendered":"\uc5d0\ub108\uc9c0\uac00 \ubd80\uc871\ud558\uba74 \ucf1c\uc9c0\ub294 \uc138\ud3ec\uc758 \ube44\uc0c1 \uc2a4\uc704\uce58, AMPK\ub294 \ubb34\uc5c7\uc778\uac00"},"content":{"rendered":"

 <\/p>\n

\"\"<\/h1>\n

ATP\uac00 \uc904\uc5b4\ub4dc\ub294 \uc21c\uac04 \uc138\ud3ec\ub294 \uc5b4\ub5bb\uac8c \uc54c\uace0, \uc65c \uc9c0\ubc29\uc744 \uc4f0\uace0 \uc131\uc7a5\uc744 \uc7a0\uc2dc \uba48\ucd9c\uae4c<\/h3>\n

\uc6b4\ub3d9\uc744 \uc624\ub798 \ud558\uac70\ub098 \ubc25\uc744 \uc624\ub7ab\ub3d9\uc548 \uba39\uc9c0 \uc54a\uc73c\uba74 \uc6b0\ub9ac \ubab8\uc5d0\uc11c\ub294 \uc218\ub9ce\uc740 \ubcc0\ud654\uac00 \uc77c\uc5b4\ub09c\ub2e4. \uc800\uc7a5\ud574 \ub450\uc5c8\ub358 \ud0c4\uc218\ud654\ubb3c\uacfc \uc9c0\ubc29\uc744 \uaebc\ub0b4 \uc4f0\uace0, \uc138\ud3ec\ub294 \ud3c9\uc18c\ubcf4\ub2e4 \uc5d0\ub108\uc9c0\ub97c \uc544\ub07c\uae30 \uc2dc\uc791\ud55c\ub2e4.<\/p>\n

\uadf8\ub807\ub2e4\uba74 \uc138\ud3ec\ub294 \uc5b4\ub5bb\uac8c \uc790\uc2e0\uc5d0\uac8c \uc5d0\ub108\uc9c0\uac00 \ubd80\uc871\ud558\ub2e4\ub294 \uc0ac\uc2e4\uc744 \uc54c\uc544\ucc28\ub9b4\uae4c.<\/p>\n

\uc138\ud3ec \uc548\uc5d0\ub294 \uc77c\uc885\uc758 \u2018\uc5d0\ub108\uc9c0 \uac10\uc9c0 \uc13c\uc11c\u2019<\/strong>\uac00 \uc874\uc7ac\ud55c\ub2e4. \uadf8 \ub300\ud45c\uc801\uc778 \uac83\uc774 \ubc14\ub85c AMPK(AMP-activated protein kinase\u00b7AMP \ud65c\uc131\ud654 \ub2e8\ubc31\uc9c8 \uc778\uc0b0\ud654\ud6a8\uc18c)<\/strong>\ub2e4.<\/p>\n

\uc774\ub984\uc740 \uc5b4\ub835\uc9c0\ub9cc \uc5ed\ud560\uc740 \uc758\uc678\ub85c \uac04\ub2e8\ud558\ub2e4.<\/p>\n

\u201c\uc9c0\uae08 \uc6b0\ub9ac \uc138\ud3ec\uc5d0 \uc5d0\ub108\uc9c0\uac00 \ucda9\ubd84\ud55c\uac00?\u201d<\/strong><\/p>\n

\uc774 \uc9c8\ubb38\uc5d0 \ub2f5\ud558\ub294 \uac83\uc774 AMPK\uc758 \uac00\uc7a5 \uc911\uc694\ud55c \uc784\ubb34\ub2e4.<\/p>\n

\uc5d0\ub108\uc9c0\uac00 \ubd80\uc871\ud574\uc9c0\uba74 AMPK\ub294 \ucf1c\uc9c0\uace0, \uc138\ud3ec\uc5d0 \uba85\ub839\ud55c\ub2e4.<\/p>\n

\u201c\uc9c0\uae08\uc740 \ub9cc\ub4dc\ub294 \ub370 \ub3c8 \uc4f0\uc9c0 \ub9c8.
\n\uc77c\ub2e8 \uc5d0\ub108\uc9c0\ub97c \ub354 \ub9cc\ub4e4\uc5b4.\u201d<\/p>\n

\uc138\ud3ec \uc218\uc900\uc5d0\uc11c \ubcf4\uba74 AMPK\ub294 \ub9d0 \uadf8\ub300\ub85c \ube44\uc0c1\uc2dc \uc804\ub825\uad00\ub9ac \uc2dc\uc2a4\ud15c<\/strong>\uc5d0 \uac00\uae5d\ub2e4. \uc2e4\uc81c\ub85c AMPK \uc5f0\uad6c\ub97c \uc624\ub7ab\ub3d9\uc548 \uc774\ub04c\uc5b4 \uc628 \uc5f0\uad6c\uc790\ub4e4\uc740 AMPK\ub97c \uc138\ud3ec\uc758 \ud575\uc2ec\uc801\uc778 \u2018energy sensor\u2019, \uc989 \uc5d0\ub108\uc9c0 \uc13c\uc11c\ub85c \uc124\uba85\ud55c\ub2e4. AMPK\ub294 ATP, ADP, AMP\uc640 \uac19\uc740 \uc5d0\ub108\uc9c0 \uad00\ub828 \ubb3c\uc9c8\uc758 \ubcc0\ud654\ub97c \uac10\uc9c0\ud558\uace0, \uc5d0\ub108\uc9c0 \uc0dd\uc0b0\uacfc \uc18c\ube44\uc758 \uade0\ud615\uc744 \uc870\uc808\ud55c\ub2e4. (Nature<\/a>)<\/p>\n

\uc6b0\ub9ac\uac00 \uc0ac\uc6a9\ud558\ub294 \uc9c4\uc9dc \uc5d0\ub108\uc9c0 \ud654\ud3d0\ub294 ATP\ub2e4<\/h2>\n

\uba3c\uc800 AMPK\ub97c \uc774\ud574\ud558\ub824\uba74 ATP\ubd80\ud130 \uc54c\uc544\uc57c \ud55c\ub2e4.<\/p>\n

\uc0ac\ub78c\uc740 \uc74c\uc2dd\uc744 \uba39\ub294\ub2e4.<\/p>\n

\ubc25\uc744 \uba39\uc73c\uba74 \ud0c4\uc218\ud654\ubb3c\uc774 \ub4e4\uc5b4\uc624\uace0, \uace0\uae30\ub97c \uba39\uc73c\uba74 \ub2e8\ubc31\uc9c8\uacfc \uc9c0\ubc29\uc774 \ub4e4\uc5b4\uc628\ub2e4. \ud558\uc9c0\ub9cc \uadfc\uc721\uc774 \ud3ec\ub3c4\ub2f9\uc774\ub098 \uc9c0\ubc29\uc744 \uadf8\ub300\ub85c \ub4e4\uace0 \uac00\uc11c \ud314\uc744 \uc6c0\uc9c1\uc774\ub294 \uac83\uc740 \uc544\ub2c8\ub2e4.<\/p>\n

\uc74c\uc2dd\uc73c\ub85c \ub4e4\uc5b4\uc628 \uc601\uc591\uc18c\ub294 \uc5ec\ub7ec \ub300\uc0ac\uacfc\uc815\uc744 \uac70\uccd0 \uacb0\uad6d ATP\ub77c\ub294 \ud615\ud0dc\uc758 \uc5d0\ub108\uc9c0<\/strong>\ub85c \uc804\ud658\ub41c\ub2e4.<\/p>\n

ATP\ub294 \ud754\ud788 \u2018\uc138\ud3ec\uc758 \uc5d0\ub108\uc9c0 \ud654\ud3d0\u2019\ub77c\uace0 \ubd88\ub9b0\ub2e4.<\/p>\n

\uc790\ub3d9\ucc28\ub85c \ube44\uc720\ud558\uba74 \ud718\ubc1c\uc720\uc640 \uc870\uae08 \ub2e4\ub974\ub2e4. \ud3ec\ub3c4\ub2f9\uacfc \uc9c0\ubc29\uc774 \uc6d0\uc720\ub098 \uc5f0\ub8cc \uc800\uc7a5\uace0\uc5d0 \uac00\uae5d\ub2e4\uba74 ATP\ub294 \ub2f9\uc7a5 \uc0ac\uc6a9\ud560 \uc218 \uc788\ub3c4\ub85d \ucda9\uc804\ub41c \ubc30\ud130\ub9ac<\/strong>\uc5d0 \uac00\uae5d\ub2e4.<\/p>\n

ATP\ub294 \u2018Adenosine Triphosphate\u2019, \uc989 \uc544\ub370\ub178\uc2e0 \uc0bc\uc778\uc0b0\uc774\ub2e4.<\/p>\n

\uc774\ub984\uc5d0\uc11c \u2018Tri\u2019\ub294 3\uc744 \uc758\ubbf8\ud55c\ub2e4.<\/p>\n

\uc989 \uc778\uc0b0(P)\uc774 \uc138 \uac1c \ubd99\uc5b4 \uc788\ub2e4.<\/p>\n

\uac04\ub2e8\ud558\uac8c \ud45c\ud604\ud558\uba74 \ub2e4\uc74c\uacfc \uac19\ub2e4.<\/p>\n

ATP \u2192 ADP + P + \uc5d0\ub108\uc9c0<\/strong><\/p>\n

ATP\uac00 \uc778\uc0b0 \ud558\ub098\ub97c \ub5bc\uc5b4\ub0b4\uba74\uc11c \uc5d0\ub108\uc9c0\ub97c \uc81c\uacf5\ud558\uba74 ADP\uac00 \ub41c\ub2e4.<\/p>\n

\uadfc\uc721\uc744 \uc218\ucd95\ud560 \ub54c\ub3c4 ATP\uac00 \uc0ac\uc6a9\ub41c\ub2e4.
\n\uc138\ud3ec \uc548\uc5d0\uc11c \ubb3c\uc9c8\uc744 \uc774\ub3d9\uc2dc\ud0ac \ub54c\ub3c4 \ud544\uc694\ud558\ub2e4.
\n\uc774\uc628 \ub18d\ub3c4\ub97c \uc720\uc9c0\ud558\ub294 \ub370\ub3c4 \ud544\uc694\ud558\ub2e4.
\n\ub2e8\ubc31\uc9c8\uc744 \ub9cc\ub4dc\ub294 \ub370\ub3c4 \uc5d0\ub108\uc9c0\uac00 \ud544\uc694\ud558\ub2e4.<\/p>\n

\uc6b0\ub9ac\uac00 \uc0b4\uc544 \uc788\ub294 \ub3d9\uc548 \uc138\ud3ec\uc5d0\uc11c\ub294 \ub04a\uc784\uc5c6\uc774 ATP\ub97c \uc0ac\uc6a9\ud558\uace0 \ub2e4\uc2dc \ub9cc\ub4e4\uc5b4\ub0b4\ub294 \uc791\uc5c5\uc774 \ubc18\ubcf5\ub41c\ub2e4.<\/p>\n

ATP\uac00 \uc904\uc5b4\ub4e4\uba74 ADP\uac00 \uc99d\uac00\ud55c\ub2e4<\/h2>\n

\uc5ec\uae30\uc11c \uc6b4\ub3d9\uc744 \uc2dc\uc791\ud588\ub2e4\uace0 \uc0dd\uac01\ud574\ubcf4\uc790.<\/p>\n

\uadfc\uc721\uc774 \ube60\ub974\uac8c \uc218\ucd95\ud558\uba74\uc11c ATP\ub97c \uacc4\uc18d \uc0ac\uc6a9\ud55c\ub2e4.<\/p>\n

ATP \u2192 ADP<\/p>\n

\uc774 \ubc18\uc751\uc774 \uacc4\uc18d \uc77c\uc5b4\ub09c\ub2e4.<\/p>\n

\uadf8\ub807\ub2e4\uace0 \uc6b4\ub3d9\uc744 \uba87 \ucd08 \ud588\ub2e4\uace0 ATP\uac00 \uc644\uc804\ud788 \uc0ac\ub77c\uc9c0\ub294 \uac83\uc740 \uc544\ub2c8\ub2e4. \uc6b0\ub9ac \ubab8\uc740 ATP \ub18d\ub3c4\ub97c \ub9e4\uc6b0 \uc911\uc694\ud558\uac8c \uad00\ub9ac\ud558\uae30 \ub54c\ubb38\uc5d0 \ud06c\ub808\uc544\ud2f4\uc778\uc0b0 \uc2dc\uc2a4\ud15c, \ud574\ub2f9\uacfc\uc815, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 \uc0b0\ud654\uc801 \uc778\uc0b0\ud654 \ub4f1\uc744 \uc774\uc6a9\ud574 \uacc4\uc18d ATP\ub97c \uc7ac\uc0dd\ud55c\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \uc5d0\ub108\uc9c0 \uc0ac\uc6a9 \uc18d\ub3c4\uac00 \uc0dd\uc0b0 \uc18d\ub3c4\ub97c \uc555\ubc15\ud558\uae30 \uc2dc\uc791\ud558\uba74 ADP\uc640 AMP \uac19\uc740 \uc2e0\ud638\uac00 \uc99d\uac00\ud55c\ub2e4.<\/strong><\/p>\n

\uc5ec\uae30\uc11c \uc911\uc694\ud55c \ubc18\uc751\uc774 \ud558\ub098 \uc788\ub2e4.<\/p>\n

2 ADP \u2194 ATP + AMP<\/strong><\/p>\n

ADP \ub450 \uac1c\ub97c \uc774\uc6a9\ud574 \ud558\ub098\ub294 ATP\ub85c \ub9cc\ub4e4\uace0, \ub098\uba38\uc9c0 \ud558\ub098\ub294 AMP\ub85c \ub9cc\ub4dc\ub294 \ubc18\uc751\uc774\ub2e4. \uc774 \uacfc\uc815\uc5d0\ub294 adenylate kinase(\uc544\ub370\ub2d0\ub808\uc774\ud2b8 \ud0a4\ub098\uc544\uc81c)<\/strong>\ub77c\ub294 \ud6a8\uc18c\uac00 \uad00\uc5ec\ud55c\ub2e4.<\/p>\n

\uadf8\ub798\uc11c \uc138\ud3ec\uac00 \uc5d0\ub108\uc9c0\ub97c \ub9ce\uc774 \uc0ac\uc6a9\ud560\uc218\ub85d AMP\uc758 \ubcc0\ud654\uac00 \ud2b9\ud788 \ubbfc\uac10\ud55c \uacbd\uace0 \uc2e0\ud638\uac00 \ub420 \uc218 \uc788\ub2e4. ATP\uac00 \uc870\uae08\ub9cc \ud754\ub4e4\ub824\ub3c4 AMP:ATP \ube44\uc728\uc740 \ub354 \ud06c\uac8c \ubcc0\ud654\ud560 \uc218 \uc788\uae30 \ub54c\ubb38\uc774\ub2e4. (\uad6d\ub9bd\uc0dd\uba85\uacf5\ud559\uc815\ubcf4\uc13c\ud130<\/a>)<\/p>\n

\uc774\ub97c \uc544\uc8fc \uc27d\uac8c \ube44\uc720\ud558\uba74 \uc774\ub807\ub2e4.<\/p>\n

ATP\ub294 \ub9cc\uc6d0\uc9dc\ub9ac \uc9c0\ud3d0<\/strong>,
\nADP\ub294 \uc0ac\uc6a9\ud558\uace0 \ub0a8\uc740 \ub3c8<\/strong>,
\nAMP\ub294 \ud1b5\uc7a5 \uc794\uc561\uc774 \uc815\ub9d0 \uc704\ud5d8\ud574\uc84c\ub2e4\ub294 \uacbd\uace0\ubb38<\/strong>\uacfc \ube44\uc2b7\ud558\ub2e4.<\/p>\n

AMPK\ub294 \uc774 \uacbd\uace0\ub97c \uac10\uc9c0\ud55c\ub2e4.<\/p>\n

AMP\uac00 \ub9ce\uc544\uc9c0\uba74 AMPK\uac00 \u201c\uc5d0\ub108\uc9c0\uac00 \ubd80\uc871\ud558\ub2e4\u201d\uace0 \ud310\ub2e8\ud55c\ub2e4<\/h2>\n

AMPK\uc758 \uc774\ub984\ubd80\ud130 \ub2e4\uc2dc \uc0b4\ud3b4\ubcf4\uc790.<\/p>\n

AMP-activated Protein Kinase<\/strong><\/p>\n

\uc989 AMP\uc640 \uad00\ub828\ud574 \ud65c\uc131\ud654\ub418\ub294 \ub2e8\ubc31\uc9c8 \uc778\uc0b0\ud654\ud6a8\uc18c\ub77c\ub294 \uc758\ubbf8\ub2e4.<\/p>\n

\uc608\uc804\uc5d0\ub294 \uc8fc\ub85c AMP\uac00 AMPK\ub97c \ucf20\ub2e4\uace0 \uc124\uba85\ud588\uc9c0\ub9cc, \ud604\uc7ac\ub294 ATP\ubfd0 \uc544\ub2c8\ub77c AMP\uc640 ADP\uc758 \uc0c1\ub300\uc801\uc778 \ubcc0\ud654\uae4c\uc9c0 \ud568\uaed8 \uac10\uc9c0\ud558\ub294 \ubcf5\uc7a1\ud55c \uc5d0\ub108\uc9c0 \uc13c\uc11c<\/strong>\ub85c \uc774\ud574\ud558\ub294 \uac83\uc774 \ub354 \uc815\ud655\ud558\ub2e4.<\/p>\n

AMPK\uc5d0\ub294 \u03b1, \u03b2, \u03b3\ub77c\ub294 \uc138 \uc885\ub958\uc758 \uc18c\ub2e8\uc704\uac00 \uc788\uace0, \ud2b9\ud788 \u03b3 \uc18c\ub2e8\uc704\uac00 ATP\u00b7ADP\u00b7AMP\uc640 \uac19\uc740 \uc544\ub370\ub2cc \ub274\ud074\ub808\uc624\ud0c0\uc774\ub4dc\uc758 \uc0c1\ud0dc\ub97c \uac10\uc9c0\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud55c\ub2e4. \uc5d0\ub108\uc9c0 \uc0c1\ud0dc\uac00 \ub5a8\uc5b4\uc9c0\uba74\uc11c AMP:ATP \ub610\ub294 ADP:ATP \ube44\uc728\uc774 \uc99d\uac00\ud558\uba74 AMPK\uac00 \ud65c\uc131\ud654\ub418\uae30 \uc26c\uc6b4 \ubc29\ud5a5\uc73c\ub85c \uc2dc\uc2a4\ud15c\uc774 \uc6c0\uc9c1\uc778\ub2e4. (Nature<\/a>)<\/p>\n

\ucd08\ub4f1\ud559\uc0dd\uc5d0\uac8c \uc124\uba85\ud55c\ub2e4\uba74 \uc774\ub807\uac8c \ub9d0\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uc138\ud3ec \uc548\uc5d0 \uc791\uc740 \uad00\ub9ac\uc2e4\uc774 \ud558\ub098 \uc788\ub2e4\uace0 \uc0dd\uac01\ud574\ubcf4\uc790.<\/p>\n

\uad00\ub9ac\uc2e4 \ubcbd\uc5d0\ub294 \ubc30\ud130\ub9ac \ud45c\uc2dc\uae30\uac00 \uc788\ub2e4.<\/p>\n

ATP \ub9ce\uc74c = \ubc30\ud130\ub9ac \ucda9\ubd84<\/strong><\/p>\n

AMP\u00b7ADP \uc99d\uac00 = \ubc30\ud130\ub9ac \ubd80\uc871 \uc2e0\ud638<\/strong><\/p>\n

\ubc30\ud130\ub9ac\uac00 \ucda9\ubd84\ud558\uba74 \uad00\ub9ac\uc2e4\uc740 \uac00\ub9cc\ud788 \uc788\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \ubc30\ud130\ub9ac \uacbd\uace0\ub4f1\uc774 \ub4e4\uc5b4\uc624\uba74 AMPK\uac00 \uc678\uce5c\ub2e4.<\/p>\n

\u201c\ube44\uc0c1 \uc0c1\ud669\uc774\ub2e4!\u201d<\/p>\n

\uadf8\ub9ac\uace0 \uc138\ud3ec\uc758 \uc6b4\uc601 \ubc29\uc2dd \uc790\uccb4\ub97c \ubc14\uafbc\ub2e4.<\/p>\n

AMPK\uac00 \ucf1c\uc9c0\uba74 \uac00\uc7a5 \uba3c\uc800 \ud558\ub294 \uc77c, \u201c\ub3c8 \ubc8c\uace0 \ub3c8 \uc4f0\uc9c0 \ub9c8\u201d<\/h2>\n

AMPK\uc758 \ud589\ub3d9 \uc6d0\uce59\uc740 \ub180\ub77c\uc6b8 \uc815\ub3c4\ub85c \ub2e8\uc21c\ud558\ub2e4.<\/p>\n

ATP\ub97c \ub9cc\ub4dc\ub294 \uacfc\uc815\uc740 \uc99d\uac00\uc2dc\ud0a4\uace0, ATP\ub97c \ub9ce\uc774 \uc18c\ube44\ud558\ub294 \uacfc\uc815\uc740 \uc904\uc778\ub2e4.<\/strong><\/p>\n

\uc0dd\ubb3c\ud559\uc5d0\uc11c\ub294 \ubb3c\uc9c8\uc744 \ubd84\ud574\ud574 \uc5d0\ub108\uc9c0\ub97c \uc5bb\ub294 \uacfc\uc815\uc744 \uc774\ud654\uc791\uc6a9(catabolism)<\/strong>\uc774\ub77c\uace0 \ud558\uace0, \uc5d0\ub108\uc9c0\ub97c \uc0ac\uc6a9\ud574 \uc0c8\ub85c\uc6b4 \ubb3c\uc9c8\uc744 \ub9cc\ub4dc\ub294 \uacfc\uc815\uc744 \ub3d9\ud654\uc791\uc6a9(anabolism)<\/strong>\uc774\ub77c\uace0 \ud55c\ub2e4.<\/p>\n

AMPK\uac00 \ud65c\uc131\ud654\ub418\uba74 \uc804\uccb4\uc801\uc73c\ub85c\ub294 \uc774\ud654\uc791\uc6a9 \ucabd\uc73c\ub85c \ubb34\uac8c\uc911\uc2ec\uc744 \uc62e\uae30\uace0, \uc5d0\ub108\uc9c0\ub97c \ub9ce\uc774 \uc18c\ube44\ud558\ub294 \ub3d9\ud654\uc791\uc6a9\uc744 \uc5b5\uc81c\ud558\ub294 \ubc29\ud5a5\uc73c\ub85c \uc791\ub3d9\ud55c\ub2e4. (Nature<\/a>)<\/p>\n

\ud68c\uc0ac\ub85c \ube44\uc720\ud558\uba74 \uc774\ud574\ud558\uae30 \uc27d\ub2e4.<\/p>\n

\ud68c\uc0ac \ud1b5\uc7a5\uc5d0 100\uc5b5 \uc6d0\uc774 \uc788\ub2e4\uba74 \uc0c8 \uac74\ubb3c\ub3c4 \uc9d3\uace0, \uacf5\uc7a5\ub3c4 \ud655\uc7a5\ud558\uace0, \uc0c8\ub85c\uc6b4 \uc124\ube44\ub3c4 \uc0b4 \uc218 \uc788\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \ud1b5\uc7a5 \uc794\uc561\uc774 \uae09\uaca9\ud788 \uc904\uc5b4\ub4e0\ub2e4\uba74 \uc5b4\ub5bb\uac8c \ud574\uc57c \ud560\uae4c.<\/p>\n

\ud22c\uc790\ub97c \uc7a0\uc2dc \uba48\ucd94\uace0 \ud604\uae08\uc744 \ud655\ubcf4\ud574\uc57c \ud55c\ub2e4.<\/p>\n

AMPK\uac00 \ud558\ub294 \uc77c\uc774 \ubc14\ub85c \uc774\uac83\uc774\ub2e4.<\/p>\n

\u201c\uac74\uc124 \uc911\ub2e8.\u201d<\/strong><\/p>\n

\u201c\ubd88\ud544\uc694\ud55c \uc0dd\uc0b0 \uc911\ub2e8.\u201d<\/strong><\/p>\n

\u201c\uc5f0\ub8cc \ud655\ubcf4.\u201d<\/strong><\/p>\n

\u201c\uc5d0\ub108\uc9c0 \uc0dd\uc0b0 \uc99d\uac00.\u201d<\/strong><\/p>\n

\uc138\ud3ec\uc758 \uc0dd\uc874\uc744 \uc704\ud574 \uc608\uc0b0\uc744 \ub2e4\uc2dc \ud3b8\uc131\ud558\ub294 \uac83\uc774\ub2e4.<\/p>\n

\uadf8\ub798\uc11c AMPK\uac00 \ucf1c\uc9c0\uba74 \uc9c0\ubc29 \uc0ac\uc6a9\uc5d0\ub3c4 \uc601\ud5a5\uc744 \uc900\ub2e4<\/h2>\n

AMPK\uac00 \uc6b4\ub3d9 \ubd84\uc57c\uc5d0\uc11c \ud2b9\ud788 \uc720\uba85\ud55c \uc774\uc720 \uac00\uc6b4\ub370 \ud558\ub098\uac00 \uc9c0\ubc29\ub300\uc0ac\uc640 \uad00\uacc4\uac00 \uc788\uae30 \ub54c\ubb38\uc774\ub2e4.<\/p>\n

AMPK\uac00 \ud65c\uc131\ud654\ub418\uba74 ACC(Acetyl-CoA Carboxylase)<\/strong>\ub77c\ub294 \ud6a8\uc18c\uc758 \ud65c\uc131\uc744 \uc5b5\uc81c\ud560 \uc218 \uc788\ub2e4.<\/p>\n

ACC\ub294 \uc9c0\ubc29\uc0b0 \ud569\uc131\uacfc \uad00\ub828\ub41c \ub300\uc0ac \uc870\uc808\uc5d0 \uc911\uc694\ud55c \ud6a8\uc18c\ub2e4.<\/p>\n

ACC\uc758 \ud65c\uc131\uc774 \uc5b5\uc81c\ub418\uba74 malonyl-CoA<\/strong>\uac00 \uac10\uc18c\ud558\ub294 \ubc29\ud5a5\uc73c\ub85c \uc6c0\uc9c1\uc774\uace0, \uc774\ub294 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub85c \uc9c0\ubc29\uc0b0\uc774 \ub4e4\uc5b4\uac00 \uc0b0\ud654\ub420 \uc218 \uc788\ub294 \ud658\uacbd\uc744 \ub9cc\ub4dc\ub294 \ub370 \uae30\uc5ec\ud55c\ub2e4.<\/p>\n

\uc27d\uac8c \ud45c\ud604\ud558\uba74 \uc774\ub7f0 \uac83\uc774\ub2e4.<\/p>\n

\ud3c9\uc18c\uc5d0\ub294 \uc9c0\ubc29 \ucc3d\uace0 \uc55e\uc5d0 \uacbd\ube44\uc6d0\uc774 \uc11c \uc788\ub2e4.<\/p>\n

\uadf8\ub7f0\ub370 \uc5d0\ub108\uc9c0\uac00 \ubd80\uc871\ud574\uc9c4\ub2e4.<\/p>\n

AMPK\uac00 \ub098\ud0c0\ub098 \ub9d0\ud55c\ub2e4.<\/p>\n

\u201c\uc9c0\uae08 \uc5f0\ub8cc\uac00 \ubd80\uc871\ud558\ub2c8\uae4c \uc800\uc7a5\ud574 \ub193\uc740 \uc9c0\ubc29\ub3c4 \uc0ac\uc6a9\ud560 \uc900\ube44\ud574.\u201d<\/p>\n

\uadf8\ub7ec\uba74\uc11c \uc9c0\ubc29\uc0b0\uc744 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc5d0\uc11c \uc5d0\ub108\uc9c0 \uc0dd\uc0b0\uc5d0 \uc774\uc6a9\ud560 \uc218 \uc788\ub3c4\ub85d \ub300\uc0ac\ud658\uacbd\uc744 \ubc14\uafb8\ub294 \uac83\uc774\ub2e4.<\/p>\n

\ub2e4\ub9cc \uc5ec\uae30\uc11c \ud754\ud788 \ud558\ub294 \uc624\ud574\uac00 \uc788\ub2e4.<\/p>\n

\u201cAMPK\uac00 \ucf1c\uc9c0\uba74 \ubb34\uc870\uac74 \uccb4\uc9c0\ubc29\uc774 \ube60\uc9c4\ub2e4\u201d\ub294 \ub73b\uc740 \uc544\ub2c8\ub2e4.<\/strong><\/p>\n

AMPK\ub294 \uc138\ud3ec\uc758 \uc5d0\ub108\uc9c0 \uc0c1\ud0dc\ub97c \uc870\uc808\ud558\ub294 \uc2e0\ud638\uccb4\uacc4\uc774\uc9c0, \uadf8 \uc790\uccb4\uac00 \uccb4\uc9c0\ubc29 \uac10\uc18c \ubc84\ud2bc\uc740 \uc544\ub2c8\ub2e4.<\/p>\n

\uc2e4\uc81c \uccb4\uc9c0\ubc29 \ubcc0\ud654\ub294 \ud558\ub8e8 \uc804\uccb4 \uc5d0\ub108\uc9c0 \uc12d\ucde8\ub7c9\uacfc \uc18c\ube44\ub7c9, \uc6b4\ub3d9\ub7c9, \uc2dd\uc0ac, \ud638\ub974\ubaac \ud658\uacbd \ub4f1 \ud6e8\uc52c \ub9ce\uc740 \uc694\uc18c\uc758 \uc601\ud5a5\uc744 \ubc1b\ub294\ub2e4.<\/p>\n

\ud3ec\ub3c4\ub2f9 \uc0ac\uc6a9\ub3c4 \uc870\uc808\ud55c\ub2e4<\/h2>\n

\uc6b4\ub3d9 \uc911\uc778 \uadfc\uc721\uc5d0\uac8c \uac00\uc7a5 \uc911\uc694\ud55c \uc5f0\ub8cc \uac00\uc6b4\ub370 \ud558\ub098\ub294 \ud3ec\ub3c4\ub2f9\uc774\ub2e4.<\/p>\n

\uadfc\uc721\uc774 \ube60\ub974\uac8c ATP\ub97c \uc0ac\uc6a9\ud558\uba74\uc11c \uc5d0\ub108\uc9c0 \uc694\uad6c\ub7c9\uc774 \uc99d\uac00\ud558\uba74 AMPK\uc640 \uc5ec\ub7ec \uc6b4\ub3d9 \uad00\ub828 \uc2e0\ud638\uccb4\uacc4\uac00 \ud65c\uc131\ud654\ub418\uace0, \uadfc\uc721\uc138\ud3ec\ub294 \ud608\uc561\uc5d0 \uc788\ub294 \ud3ec\ub3c4\ub2f9\uc744 \ub354 \uc801\uadf9\uc801\uc73c\ub85c \uc0ac\uc6a9\ud560 \uc218 \uc788\ub3c4\ub85d \ubc18\uc751\ud55c\ub2e4.<\/p>\n

\uc989 \uc6b4\ub3d9\ud560 \ub54c \uadfc\uc721\uc740 \ub2e8\uc21c\ud788 \u201c\uce7c\ub85c\ub9ac\ub97c \ud0dc\uc6b0\ub294 \uac83\u201d\uc774 \uc544\ub2c8\ub2e4.<\/p>\n

\uc138\ud3ec \ub0b4\ubd80\uc5d0\uc11c\ub294 \uacc4\uc18d \uc774\ub7f0 \ub300\ud654\uac00 \uc624\uac04\ub2e4.<\/p>\n

\u201cATP \uc0ac\uc6a9\ub7c9 \uc99d\uac00!\u201d<\/p>\n

\u201c\uc5d0\ub108\uc9c0 \uc218\uc694 \uc99d\uac00!\u201d<\/p>\n

\u201c\uc5f0\ub8cc \ub354 \ud544\uc694!\u201d<\/p>\n

\u201c\ud3ec\ub3c4\ub2f9 \ud655\ubcf4!\u201d<\/p>\n

\u201c\uc9c0\ubc29\uc0b0 \ud65c\uc6a9!\u201d<\/p>\n

\u201c\ubd88\ud544\uc694\ud55c \uc5d0\ub108\uc9c0 \uc18c\ube44 \uac10\uc18c!\u201d<\/p>\n

AMPK\ub294 \uc774\ub7f0 \uac70\ub300\ud55c \uc5d0\ub108\uc9c0 \uc870\uc808\ub9dd\uc5d0\uc11c \uc911\uc694\ud55c \uc911\uc559 \uc2e0\ud638 \uac00\uc6b4\ub370 \ud558\ub098\ub2e4.<\/p>\n

\uadf8\ub807\ub2e4\uba74 AMPK\uc640 mTOR\ub294 \uc65c \uc790\uc8fc \ud568\uaed8 \ub4f1\uc7a5\ud560\uae4c<\/h2>\n

\uc6b4\ub3d9\uacfc \uadfc\ube44\ub300\ub97c \uacf5\ubd80\ud558\ub2e4 \ubcf4\uba74 AMPK\uc640 \ud568\uaed8 \uac70\uc758 \ubc18\ub4dc\uc2dc \ub4f1\uc7a5\ud558\ub294 \uc774\ub984\uc774 \uc788\ub2e4.<\/p>\n

\ubc14\ub85c mTOR<\/strong>\ub2e4.<\/p>\n

\uc544\uc8fc \ub2e8\uc21c\ud558\uac8c \uc124\uba85\ud558\uba74 mTOR\ub294 \uc138\ud3ec\uc5d0 \uc774\ub807\uac8c \ub9d0\ud558\ub294 \uc2dc\uc2a4\ud15c\uc5d0 \uac00\uae5d\ub2e4.<\/p>\n

\u201c\uc7ac\ub8cc\ub3c4 \uc788\uace0 \uc5d0\ub108\uc9c0\ub3c4 \uc788\uc73c\ub2c8 \ub9cc\ub4e4\uc790.\u201d<\/strong><\/p>\n

\ub2e8\ubc31\uc9c8 \ud569\uc131, \uc131\uc7a5\uacfc \uad00\ub828\ub41c \uc5ec\ub7ec \uc2e0\ud638\ub97c \uc870\uc808\ud55c\ub2e4.<\/p>\n

\ubc18\ub300\ub85c AMPK\ub294 \uc774\ub807\uac8c \ub9d0\ud55c\ub2e4.<\/p>\n

\u201c\uc9c0\uae08 \uc5d0\ub108\uc9c0\uac00 \ubd80\uc871\ud558\ub2c8 \uc77c\ub2e8 \uc0b4\uc544\ub0a8\ub294 \ub370 \uc9d1\uc911\ud558\uc790.\u201d<\/strong><\/p>\n

\uadf8\ub798\uc11c \ub450 \uc2dc\uc2a4\ud15c\uc740 \uc5ec\ub7ec \uc9c0\uc810\uc5d0\uc11c \uc11c\ub85c \ubc18\ub300 \ubc29\ud5a5\uc73c\ub85c \uc791\uc6a9\ud560 \uc218 \uc788\ub2e4.<\/p>\n

AMPK\uac00 \uac15\ud558\uac8c \ud65c\uc131\ud654\ub418\uba74 TSC2\ub098 Raptor \ub4f1\uc744 \ud1b5\ud574 mTORC1 \uc2e0\ud638\ub97c \uc5b5\uc81c\ud558\ub294 \ubc29\ud5a5<\/strong>\uc73c\ub85c \uc791\uc6a9\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uc774\uac83\ub3c4 \uacf5\uc7a5\uc73c\ub85c \uc0dd\uac01\ud558\uba74 \ub9e4\uc6b0 \uc27d\ub2e4.<\/p>\n

mTOR\ub294 \uacf5\uc7a5 \uc99d\uc124\ud300\uc774\ub2e4.<\/p>\n

\u201c\uacf5\uc7a5 \ud558\ub098 \ub354 \uc9d3\uaca0\uc2b5\ub2c8\ub2e4!\u201d<\/p>\n

AMPK\ub294 \uc7ac\ubb34\ud300\uc774\ub2e4.<\/p>\n

\uadf8\ub7f0\ub370 \ud68c\uc0ac\uc5d0 \ub3c8\uc774 \uc5c6\ub2e4.<\/p>\n

\uc7ac\ubb34\ud300\uc774 \ub9d0\ud55c\ub2e4.<\/p>\n

\u201c\uc9c0\uae08 \ud1b5\uc7a5\uc5d0 \ub3c8 \uc5c6\ub294\ub370 \ubb34\uc2a8 \uacf5\uc7a5\uc744 \uc9c0\uc5b4. \uc77c\ub2e8 \uc911\ub2e8.\u201d<\/p>\n

\uc774\uac83\uc774 AMPK\uc640 mTOR\uc758 \uae30\ubcf8\uc801\uc778 \uad00\uacc4\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \ub450 \uc2dc\uc2a4\ud15c\uc744 \ub2e8\uc21c\ud788 \u2018AMPK\ub294 \ub098\uc05c \uac83, mTOR\ub294 \uc88b\uc740 \uac83\u2019\uc73c\ub85c \uc774\ud574\ud574\uc11c\ub294 \uc548 \ub41c\ub2e4.<\/p>\n

\ub458 \ub2e4 \ud544\uc694\ud558\ub2e4.<\/p>\n

\uc5d0\ub108\uc9c0\uac00 \ucda9\ubd84\ud558\uace0 \uc131\uc7a5\ud574\uc57c \ud560 \ub54c\ub294 \ud569\uc131\uc774 \ud544\uc694\ud558\uace0, \uc5d0\ub108\uc9c0\uac00 \ubd80\uc871\ud560 \ub54c\ub294 \uc18c\ube44\ub97c \uc904\uc774\uace0 \uc0dd\uc0b0\uc744 \ub298\ub9ac\ub294 \uac83\uc774 \ud544\uc694\ud558\ub2e4.<\/p>\n

\uc138\ud3ec\ub294 \ub450 \uc2e0\ud638\ub97c \uc0c1\ud669\uc5d0 \ub9de\uac8c \uc870\uc808\ud55c\ub2e4.<\/p>\n

\uc6b4\ub3d9\uc744 \ud558\uba74 \uc65c AMPK\uac00 \ud65c\uc131\ud654\ub420\uae4c<\/h2>\n

\uc6b4\ub3d9\ud560 \ub54c \uadfc\uc721\uc5d0\uc11c\ub294 ATP \uc0ac\uc6a9\ub7c9\uc774 \uae09\uaca9\ud558\uac8c \uc99d\uac00\ud55c\ub2e4.<\/p>\n

\ud2b9\ud788 \uc6b4\ub3d9 \uac15\ub3c4\uac00 \ub192\uac70\ub098 \uc9c0\uc18d\uc2dc\uac04\uc774 \uae38\uc5b4\uc838 ATP \uc694\uad6c\ub7c9\uc774 \ucee4\uc9c0\uba74 \uc138\ud3ec\uc758 \uc5d0\ub108\uc9c0 \uc0c1\ud0dc\uac00 \ubcc0\ud55c\ub2e4.<\/p>\n

ATP\uac00 \uc0ac\uc6a9\ub418\uba74\uc11c ADP\uc640 AMP \uad00\ub828 \uc2e0\ud638\uac00 \ubcc0\ud654\ud558\uace0, \uc774\uac83\uc774 AMPK \ud65c\uc131\uc5d0 \uc601\ud5a5\uc744 \uc900\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \uc911\uc694\ud55c \uc810\uc774 \uc788\ub2e4.<\/p>\n

AMPK\uac00 \ub2e8\uc21c\ud788 \u2018ATP\uac00 \ub5a8\uc5b4\uc9c0\uba74 \uc790\ub3d9\uc73c\ub85c \ucf1c\uc9c0\ub294 \uc2a4\uc704\uce58\u2019\ub9cc\uc740 \uc544\ub2c8\ub2e4.<\/strong><\/p>\n

\ucd5c\uadfc \uc5f0\uad6c\uc5d0\uc11c\ub294 AMPK\uac00 AMP\u00b7ADP\u00b7ATP \ubcc0\ud654\ubfd0 \uc544\ub2c8\ub77c \ud3ec\ub3c4\ub2f9\uacfc \uae00\ub9ac\ucf54\uac90\uc758 \uc0c1\ud0dc, \uc9c0\ubc29\uc0b0 \uc0c1\ud0dc, \uc138\ud3ec \ub0b4 \uce7c\uc298 \uc2e0\ud638 \ub4f1 \ub2e4\uc591\ud55c \uc815\ubcf4\ub97c \ubc1b\uc544\ub4e4\uc774\ub294 \ud6e8\uc52c \ubcf5\uc7a1\ud55c \uc13c\uc11c\ub77c\ub294 \uc0ac\uc2e4\uc774 \ubc1d\ud600\uc9c0\uace0 \uc788\ub2e4. (Nature<\/a>)<\/p>\n

\uc989 AMPK\ub294 \ub2e8\uc21c\ud55c \ubc30\ud130\ub9ac \uc794\ub7c9\uacc4\uac00 \uc544\ub2c8\ub77c \uc5ec\ub7ec \uc13c\uc11c\ub97c \uc5f0\uacb0\ud574 \ub193\uc740 \uc2a4\ub9c8\ud2b8 \uc5d0\ub108\uc9c0 \uad00\ub9ac \uc2dc\uc2a4\ud15c<\/strong>\uc5d0 \ub354 \uac00\uae5d\ub2e4.<\/p>\n

\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc640\ub3c4 \uae4a\uc740 \uad00\uacc4\uac00 \uc788\ub2e4<\/h2>\n

AMPK \uc774\uc57c\uae30\uc5d0 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub97c \ube7c\ub193\uc744 \uc218 \uc5c6\ub2e4.<\/p>\n

\ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\ub294 \uc138\ud3ec\uac00 \uc0b0\uc18c\ub97c \uc774\uc6a9\ud574 ATP\ub97c \uc0dd\uc0b0\ud558\ub294 \ud575\uc2ec \uc7a5\uc18c\ub2e4.<\/p>\n

\uc138\ud3ec\uac00 \uc624\ub7ab\ub3d9\uc548 \uc5d0\ub108\uc9c0\ub97c \ub9ce\uc774 \uc0ac\uc6a9\ud55c\ub2e4\uba74 \ub2e8\uc21c\ud788 \uc5f0\ub8cc\ub9cc \ub354 \uac00\uc838\uc624\ub294 \uac83\uc73c\ub85c\ub294 \ubd80\uc871\ud558\ub2e4.<\/p>\n

\uc7a5\uae30\uc801\uc73c\ub85c\ub294 \uc5d0\ub108\uc9c0\ub97c \ub9cc\ub4e4\uc5b4\ub0bc \uc218 \uc788\ub294 \uc2dc\uc2a4\ud15c \uc790\uccb4\ub97c \uad00\ub9ac\ud574\uc57c \ud55c\ub2e4.<\/p>\n

AMPK\ub294 \uc774\ub7f0 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 \ud488\uc9c8 \uad00\ub9ac\uc640 \uc801\uc751\uc5d0\ub3c4 \uad00\ub828\ub41c\ub2e4.<\/p>\n

\uc190\uc0c1\ub41c \uc138\ud3ec \uad6c\uc131 \uc694\uc18c\ub97c \uc81c\uac70\ud558\ub294 autophagy(\uc790\uac00\ud3ec\uc2dd)<\/strong> \uad00\ub828 \uc2e0\ud638\uc5d0\ub3c4 \uc601\ud5a5\uc744 \ubbf8\uce58\uba70, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544\uc758 \ubd84\uc5f4\uacfc \uc81c\uac70, \uc0c8\ub85c\uc6b4 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ud615\uc131\uacfc \uad00\ub828\ub41c \uc870\uc808\ub9dd\uc5d0\ub3c4 \uad00\uc5ec\ud55c\ub2e4. \uc774\ub7f0 \uc774\uc720\ub85c \uc5f0\uad6c\uc790\ub4e4\uc740 AMPK\ub97c \ub2e8\uc21c\ud55c \uc5d0\ub108\uc9c0 \uac10\uc9c0\ud6a8\uc18c\ub97c \ub118\uc5b4 \u2018\ub300\uc0ac\uc640 \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \ud56d\uc0c1\uc131\uc744 \uc9c0\ud0a4\ub294 \uc870\uc808\uc790\u2019\ub85c \uc124\uba85\ud558\uae30\ub3c4 \ud55c\ub2e4. (Nature<\/a>)<\/p>\n

\uacb0\uad6d AMPK\uc758 \ubaa9\uc801\uc740 \ud558\ub098\ub2e4<\/h2>\n

AMPK\uc5d0 \uad00\ud55c \ub0b4\uc6a9\uc744 \ud55c \ubb38\uc7a5\uc73c\ub85c \uc555\ucd95\ud558\uba74 \ub2e4\uc74c\uacfc \uac19\ub2e4.<\/p>\n

\u201c\uc5d0\ub108\uc9c0\uac00 \ubd80\uc871\ud558\ub2e4\ub294 \uc2e0\ud638\ub97c \uac10\uc9c0\ud558\uba74, \uc5d0\ub108\uc9c0\ub97c \ub9cc\ub4dc\ub294 \ud65c\ub3d9\uc744 \ub298\ub9ac\uace0 \uc5d0\ub108\uc9c0\ub97c \ub9ce\uc774 \uc0ac\uc6a9\ud558\ub294 \ud65c\ub3d9\uc744 \uc904\uc5ec ATP\ub97c \uc9c0\ud0a4\ub294 \uc2dc\uc2a4\ud15c.\u201d<\/strong><\/p>\n

\uc804\uccb4 \ud750\ub984\uc744 \uc5f0\uacb0\ud558\uba74 \ub354\uc6b1 \uac04\ub2e8\ud558\ub2e4.<\/p>\n

\uc74c\uc2dd\uc5d0\uc11c \uc601\uc591\uc18c\ub97c \uc5bb\ub294\ub2e4.<\/p>\n

\u2193<\/p>\n

\ud3ec\ub3c4\ub2f9\uacfc \uc9c0\ubc29 \ub4f1\uc744 \uc774\uc6a9\ud574 ATP\ub97c \ub9cc\ub4e0\ub2e4.<\/p>\n

\u2193<\/p>\n

\uadfc\uc721\uc218\ucd95 \ub4f1\uc73c\ub85c ATP\ub97c \uc0ac\uc6a9\ud55c\ub2e4.<\/p>\n

\u2193<\/p>\n

ATP \u2192 ADP + P<\/strong><\/p>\n

\u2193<\/p>\n

\uc5d0\ub108\uc9c0 \uc18c\ube44\uac00 \ucee4\uc9c0\uba74\uc11c ADP\u00b7AMP \uad00\ub828 \uc2e0\ud638\uac00 \uc99d\uac00\ud55c\ub2e4.<\/p>\n

\u2193<\/p>\n

AMPK\uac00 \uc5d0\ub108\uc9c0 \ubd80\uc871 \uc0c1\ud0dc\ub97c \uac10\uc9c0\ud55c\ub2e4.<\/strong><\/p>\n

\u2193<\/p>\n

\ud3ec\ub3c4\ub2f9\u00b7\uc9c0\ubc29 \ub4f1 \uc5d0\ub108\uc9c0 \uc0dd\uc0b0\uc5d0 \uc720\ub9ac\ud55c \ub300\uc0ac\uacbd\ub85c\ub97c \ud65c\uc131\ud654\ud55c\ub2e4.<\/p>\n

\u2193<\/p>\n

\uc9c0\ubc29\u00b7\ub2e8\ubc31\uc9c8 \ub4f1 \uc5d0\ub108\uc9c0\uac00 \ub9ce\uc774 \ud544\uc694\ud55c \ud569\uc131\uacfc \uc131\uc7a5 \uad00\ub828 \uacfc\uc815\uc740 \uc77c\ubd80 \uc5b5\uc81c\ud55c\ub2e4.<\/p>\n

\u2193<\/p>\n

ATP \uc0dd\uc0b0\uacfc \uc18c\ube44\uc758 \uade0\ud615\uc744 \ub2e4\uc2dc \ub9de\ucd98\ub2e4.<\/p>\n

\uc774\ub97c \ud55c\ub9c8\ub514\ub85c \ud45c\ud604\ud558\uba74,<\/p>\n

AMPK = \uc138\ud3ec\uc758 \uc5d0\ub108\uc9c0 \uc808\uc57d \ubaa8\ub4dc\uc774\uc790 \ube44\uc0c1 \ubc1c\uc804 \uc2dc\uc2a4\ud15c<\/strong><\/p>\n

\uc774\ub77c\uace0 \ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uc2a4\ub9c8\ud2b8\ud3f0\uc758 \ubc30\ud130\ub9ac\uac00 80%\uc77c \ub54c\ub294 \ud654\uba74\ub3c4 \ubc1d\uac8c \ud558\uace0 \uc5ec\ub7ec \uc571\uc744 \ub3d9\uc2dc\uc5d0 \uc2e4\ud589\ud574\ub3c4 \ubb38\uc81c\uac00 \uc5c6\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \ubc30\ud130\ub9ac\uac00 5%\uac00 \ub418\uba74 \uc808\uc804\ubaa8\ub4dc\uac00 \ucf1c\uc9c4\ub2e4.<\/p>\n

\ud654\uba74 \ubc1d\uae30\ub97c \ub0ae\ucd94\uace0, \ubc31\uadf8\ub77c\uc6b4\ub4dc \uc791\uc5c5\uc744 \uc81c\ud55c\ud558\uace0, \uaf2d \ud544\uc694\ud55c \uae30\ub2a5\ub9cc \ub0a8\uae34\ub2e4.<\/p>\n

\uc6b0\ub9ac \uc138\ud3ec\uc5d0\ub3c4 \ube44\uc2b7\ud55c \uc2dc\uc2a4\ud15c\uc774 \uc788\ub2e4.<\/p>\n

\uadf8 \uc911\uc2ec\uc5d0 AMPK\uac00 \uc788\ub2e4.<\/p>\n

\uadf8\ub9ac\uace0 \uc6b4\ub3d9\uc0dd\ub9ac\ud559\uc5d0\uc11c AMPK\uac00 \uc911\uc694\ud55c \uc774\uc720\ub294 \ubc14\ub85c \uc774 \ub54c\ubb38\uc774\ub2e4.<\/p>\n

\uc6b4\ub3d9\uc740 \ub2e8\uc21c\ud788 \uadfc\uc721\uc744 \uc6c0\uc9c1\uc774\ub294 \ud589\uc704\uac00 \uc544\ub2c8\ub2e4.<\/p>\n

\uadfc\uc721\uc774 ATP\ub97c \uc18c\ube44\ud558\ub294 \uc21c\uac04 \uc138\ud3ec \ub0b4\ubd80\uc758 \uc5d0\ub108\uc9c0 \uc0c1\ud669\uc774 \ubcc0\ud558\uace0, \uadf8 \ubcc0\ud654\ub97c \uac10\uc9c0\ud55c AMPK\ub97c \ube44\ub86f\ud55c \ub2e4\uc591\ud55c \uc2e0\ud638\uccb4\uacc4\uac00 \ud3ec\ub3c4\ub2f9 \uc774\uc6a9, \uc9c0\ubc29\uc0b0 \uc0b0\ud654, \ubbf8\ud1a0\ucf58\ub4dc\ub9ac\uc544 \uc801\uc751, \ub2e8\ubc31\uc9c8 \ud569\uc131\uacfc \uc131\uc7a5 \uc2e0\ud638\uae4c\uc9c0 \ubcc0\ud654\uc2dc\ud0a8\ub2e4.<\/p>\n

\ub530\ub77c\uc11c AMPK\ub97c \uc774\ud574\ud55c\ub2e4\ub294 \uac83\uc740 \ub2e8\uc21c\ud788 \ud6a8\uc18c \ud558\ub098\ub97c \uacf5\ubd80\ud558\ub294 \uac83\uc774 \uc544\ub2c8\ub2e4.<\/p>\n

\uc6b0\ub9ac \ubab8\uc774 \u201c\uc5d0\ub108\uc9c0\uac00 \ubd80\uc871\ud558\ub2e4\u201d\ub294 \uc0ac\uc2e4\uc744 \uc5b4\ub5bb\uac8c \uc54c\uc544\ucc44\uace0, \uadf8 \uc21c\uac04 \uc138\ud3ec\uc758 \uacbd\uc81c\uc815\ucc45\uc744 \uc5b4\ub5bb\uac8c \ubc14\uafb8\ub294\uc9c0\ub97c \uc774\ud574\ud558\ub294 \uac83<\/strong>\uc774\ub77c\uace0 \ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uc774 \uae00\uc758 \ud575\uc2ec\uc740 ATP \uc0ac\uc6a9 \u2192 ADP\u00b7AMP \uc2e0\ud638 \ubcc0\ud654 \u2192 AMPK \ud65c\uc131 \u2192 \uc5d0\ub108\uc9c0 \uc0dd\uc0b0 \u2191 \/ \uc5d0\ub108\uc9c0 \uc18c\ube44\uc131 \ud569\uc131 \u2193<\/code><\/strong> \uc774 \ud750\ub984\uc785\ub2c8\ub2e4. \ud2b9\ud788 \ub2e4\uc74c \ub2e8\uacc4\ub85c AMPK\uc640 mTOR\uac00 \uadfc\ube44\ub300\u00b7\uadfc\ub825\u00b7\uc9c0\uad6c\ub825 \uc6b4\ub3d9\uc5d0\uc11c \uc65c \uc11c\ub85c \ub2e4\ub978 \ube44\uc728\ub85c \ub098\ud0c0\ub098\ub294\uc9c0<\/strong>\uae4c\uc9c0 \uc5f0\uacb0\ud558\uba74, \uc804\uc5d0 \uad81\uae08\ud574\ud558\uc168\ub358 \u201c\ub611\uac19\uc774 \uc6b4\ub3d9\ud574\uc11c \uc138\ud3ec\uc5d0 \uc790\uadf9\uc774 \uac00\ub294\ub370 \uc138\ud3ec\ub294 \uc5b4\ub5bb\uac8c \uc6b4\ub3d9 \uc885\ub958\ub97c \uad6c\ubd84\ud558\ub290\ub0d0\u201d\ub3c4 \uc0c1\ub2f9\ud788 \uae54\ub054\ud558\uac8c \uc124\uba85\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n","protected":false},"excerpt":{"rendered":"

  ATP\uac00 \uc904\uc5b4\ub4dc\ub294 \uc21c\uac04 \uc138\ud3ec\ub294 \uc5b4\ub5bb\uac8c \uc54c\uace0, \uc65c \uc9c0\ubc29\uc744 \uc4f0\uace0 \uc131\uc7a5\uc744 \uc7a0\uc2dc \uba48\ucd9c\uae4c \uc6b4\ub3d9\uc744 \uc624\ub798 \ud558\uac70\ub098 \ubc25\uc744 \uc624\ub7ab\ub3d9\uc548 \uba39\uc9c0 \uc54a\uc73c\uba74 \uc6b0\ub9ac \ubab8\uc5d0\uc11c\ub294 \uc218\ub9ce\uc740 \ubcc0\ud654\uac00 \uc77c\uc5b4\ub09c\ub2e4. \uc800\uc7a5\ud574 \ub450\uc5c8\ub358 \ud0c4\uc218\ud654\ubb3c\uacfc \uc9c0\ubc29\uc744 \uaebc\ub0b4 \uc4f0\uace0, \uc138\ud3ec\ub294 \ud3c9\uc18c\ubcf4\ub2e4 \uc5d0\ub108\uc9c0\ub97c \uc544\ub07c\uae30 \uc2dc\uc791\ud55c\ub2e4. \uadf8\ub807\ub2e4\uba74 \uc138\ud3ec\ub294 \uc5b4\ub5bb\uac8c \uc790\uc2e0\uc5d0\uac8c \uc5d0\ub108\uc9c0\uac00 \ubd80\uc871\ud558\ub2e4\ub294 \uc0ac\uc2e4\uc744 \uc54c\uc544\ucc28\ub9b4\uae4c. \uc138\ud3ec \uc548\uc5d0\ub294 \uc77c\uc885\uc758 \u2018\uc5d0\ub108\uc9c0 \uac10\uc9c0 \uc13c\uc11c\u2019\uac00 \uc874\uc7ac\ud55c\ub2e4. \uadf8 \ub300\ud45c\uc801\uc778 \uac83\uc774 \ubc14\ub85c […]<\/p>\n","protected":false},"author":401,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,14,40,39,42],"tags":[],"class_list":["post-1833","post","type-post","status-publish","format-standard","hentry","category-3","category-14","category-40","category-39","category-42"],"_links":{"self":[{"href":"https:\/\/rhanews.co.kr\/index.php?rest_route=\/wp\/v2\/posts\/1833","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rhanews.co.kr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rhanews.co.kr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rhanews.co.kr\/index.php?rest_route=\/wp\/v2\/users\/401"}],"replies":[{"embeddable":true,"href":"https:\/\/rhanews.co.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1833"}],"version-history":[{"count":1,"href":"https:\/\/rhanews.co.kr\/index.php?rest_route=\/wp\/v2\/posts\/1833\/revisions"}],"predecessor-version":[{"id":1835,"href":"https:\/\/rhanews.co.kr\/index.php?rest_route=\/wp\/v2\/posts\/1833\/revisions\/1835"}],"wp:attachment":[{"href":"https:\/\/rhanews.co.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1833"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rhanews.co.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1833"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rhanews.co.kr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1833"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}